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1

Genome editing in plants by engineered CRISPR–Cas9 recognizing NG PAM

Endo, Masaki, Mikami, Masafumi, Endo, Akira, Kaya, Hidetaka, Itoh, Takeshi, Nishimasu, Hiroshi, Nureki, Osamu, Toki, Seiichi

Journal:

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

2

CHIME age dating of monazites from metamorphic rocks and granitic rocks of the Ryoke belt in the Iwakuni area, Southwest Japan

Kazuhiro Suzuki, Mamoru Adachi, Terukazu Nureki

Journal:

Year:

1996

Language:

english

File:

PDF, 1.19 MB

english, 1996

3

Enzyme Structure with Two Catalytic Sites for Double-Sieve Selection of Substrate

Journal:

Year:

1998

Language:

english

File:

PDF, 606 KB

english, 1998

4

Crystal Structure of a Claudin Provides Insight into the Architecture of Tight Junctions

Suzuki, H., Nishizawa, T., Tani, K., Yamazaki, Y., Tamura, A., Ishitani, R., Dohmae, N., Tsukita, S., Nureki, O., Fujiyoshi, Y.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

5

Cyclic GMP–AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

Kato, Kazuki, Omura, Hiroki, Ishitani, Ryuichiro, Nureki, Osamu

Journal:

Annual Review of Biochemistry

Year:

2017

Language:

english

File:

PDF, 6.04 MB

english, 2017

6

10.1038/19242

Yokoyama, Shigeyuki, Handa, Noriko, Nureki, Osamu, Kurimoto, Kazuki, Kim, Insil, Sakamoto, Hiroshi, Shimura, Yoshiro, Muto, Yutaka

Journal:

Year:

1999

Language:

english

File:

PDF, 647 KB

english, 1999

7

The 2.0 Å crystal structure of Thermus thermophilus methionyl-tRNA synthetase reveals two RNA-binding modules

Ikuko Sugiura, Osamu Nureki, Yoshiko Ugaji-Yoshikawa, Sachiko Kuwabara, Atsushi Shimada, Masaru Tateno, Bernard Lorber, Richard Giegé, Dino Moras, Shigeyuki Yokoyama, Michiko Konno

Journal:

Year:

2000

Language:

english

File:

PDF, 467 KB

english, 2000

8

Structural Basis for Double-Sieve Discrimination of L-Valine from L-Isoleucine and L-Threonine by the Complex of tRNAVal and Valyl-tRNA Synthetase

Shuya Fukai, Osamu Nureki, Shun-ichi Sekine, Atsushi Shimada, Jianshi Tao, Dmitry G. Vassylyev, Shigeyuki Yokoyama

Journal:

Year:

2000

Language:

english

File:

PDF, 1.23 MB

english, 2000

9

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

Nishimasu, Hiroshi, Ran, F. Ann, Hsu, Patrick D., Konermann, Silvana, Shehata, Soraya I., Dohmae, Naoshi, Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu

Journal:

Year:

2014

Language:

english

File:

PDF, 5.97 MB

english, 2014

10

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Joung, Julia, Abudayyeh, Omar O., Barcena, Clea, Hsu, Patrick D., Habib, Naomi, Gootenberg, Jonathan S., Nishimasu, Hiroshi, Nureki, Osamu,

Journal:

Year:

2014

Language:

english

File:

PDF, 6.46 MB

english, 2014

11

Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation

Araiso, Y., Palioura, S., Ishitani, R., Sherrer, R. L., O'Donoghue, P., Yuan, J., Oshikane, H., Domae, N., DeFranco, J., Soll, D., Nureki, O.

Journal:

Nucleic Acids Research

Year:

2007

Language:

english

File:

PDF, 11.47 MB

english, 2007

12

Crystal Structure of Staphylococcus aureus Cas9

Nishimasu, Hiroshi, Cong, Le, Yan, Winston X., Ran, F. Ann, Zetsche, Bernd, Li, Yinqing, Kurabayashi, Arisa, Ishitani, Ryuichiro, Zhang, Feng, Nureki, Osamu

Journal:

Year:

2015

Language:

english

File:

PDF, 7.99 MB

english, 2015

13

Engineered Cpf1 variants with altered PAM specificities

Gao, Linyi, Cox, David B T, Yan, Winston X, Manteiga, John C, Schneider, Martin W, Yamano, Takashi, Nishimasu, Hiroshi, Nureki, Osamu, Crosetto, Nicola, Zhang, Feng

Journal:

Nature Biotechnology

Year:

2017

Language:

english

File:

PDF, 3.04 MB

english, 2017

14

Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity

Lee, Yongchan, Nishizawa, Tomohiro, Takemoto, Mizuki, Kumazaki, Kaoru, Yamashita, Keitaro, Hirata, Kunio, Minoda, Ayumi, Nagatoishi, Satoru, Tsumoto, Kouhei, Ishitani, Ryuichiro, Nureki, Osamu

Journal:

Year:

2017

Language:

english

File:

PDF, 3.41 MB

english, 2017

15

Free Energy Landscape for the Entire Transport Cycle of Triose-Phosphate/Phosphate Translocator

Takemoto, Mizuki, Lee, Yongchan, Ishitani, Ryuichiro, Nureki, Osamu

Journal:

Year:

2018

Language:

english

File:

PDF, 9.67 MB

english, 2018

16

Cap-specific terminal N 6 -methylation of RNA by an RNA polymerase II–associated methyltransferase

Akichika, Shinichiro, Hirano, Seiichi, Shichino, Yuichi, Suzuki, Takeo, Nishimasu, Hiroshi, Ishitani, Ryuichiro, Sugita, Ai, Hirose, Yutaka, Iwasaki, Shintaro, Nureki, Osamu, Suzuki, Tsutomu

Journal:

Year:

2018

Language:

english

File:

PDF, 2.55 MB

english, 2018

17

Crystal structure of plant vacuolar iron transporter VIT1

Kato, Takafumi, Kumazaki, Kaoru, Wada, Miki, Taniguchi, Reiya, Nakane, Takanori, Yamashita, Keitaro, Hirata, Kunio, Ishitani, Ryuichiro, Ito, Koichi, Nishizawa, Tomohiro, Nureki, Osamu

Journal:

Year:

2019

Language:

english

File:

PDF, 2.31 MB

english, 2019

18

Factors associated with false negative interferon-Î³ release assay results in patients with tuberculosis: A systematic review with meta-analysis

Yamasue, Mari, Komiya, Kosaku, Usagawa, Yuko, Umeki, Kenji, Nureki, Shin-ichi, Ando, Masaru, Hiramatsu, Kazufumi, Nagai, Hideaki, Kadota, Jun-ichi

Journal:

Scientific Reports

Year:

2020

Language:

english

File:

PDF, 1.90 MB

english, 2020

19

Influence of the mucin coat on the survival of rabbit and mouse embryos stored at 0°c

M. Kasai, M. Hiraishi, I. Nureki, S. E. Zhu, T. Sakurai, T. Machida

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1993

Language:

english

File:

PDF, 639 KB

english, 1993

20

Use of layer silicate for protein crystallization: Effects of Micromica and chlorite powders in hanging drops

Masahide Takehara, Keita Ino, Yoichi Takakusagi, Hiroyuki Oshikane, Osamu Nureki, Takeo Ebina, Fujio Mizukami, Kengo Sakaguchi

Journal:

Analytical Biochemistry

Year:

2008

Language:

english

File:

PDF, 616 KB

english, 2008

21

Role of ADAM8 in experimental asthma

Osamu Matsuno, Eishi Miyazaki, Shinichi Nureki, Takuya Ueno, Toshihide Kumamoto, Yasunori Higuchi

Journal:

Immunology Letters

Year:

2006

Language:

english

File:

PDF, 475 KB

english, 2006

22

Continental basalts in the accretionary complexes of the South-west Japan Arc: Constraints from geochemical and Sr and Nd isotopic data of metadiabase

Hiroo Kagami, Masaki Yuhara, Shigeru Iizumi, Yoshiaki Tainosho, Masaaki Owada, Yasuo Ikeda, Osamu Okano, Shuji Ochi, Yoshikazu Hayama, Terukazu Nureki

Journal:

Year:

2000

Language:

english

File:

PDF, 1.32 MB

english, 2000

23

Crystal structure of a putative aspartate aminotransferase belonging to subgroup IV

Yasuhiro Katsura, Mikako Shirouzu, Hiroto Yamaguchi, Ryuichiro Ishitani, Osamu Nureki, Seiki Kuramitsu, Hideyuki Hayashi, Shigeyuki Yokoyama

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2004

Language:

english

File:

PDF, 1.32 MB

english, 2004

24

Crystal structure of the cytosolic domain of the cation diffusion facilitator family protein

Takashi Higuchi, Motoyuki Hattori, Yoshiki Tanaka, Ryuichiro Ishitani, Osamu Nureki

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 223 KB

english, 2009

25

Significance of Serum Vascular Endothelial Growth Factor Level in Patients with Idiopathic Pulmonary Fibrosis

Masaru Ando, Eishi Miyazaki, Takeo Ito, Shigeo Hiroshige, Shin-ich Nureki, Takuya Ueno, Ryuichi Takenaka, Tetsujiro Fukami, Toshihide Kumamoto

Journal:

Year:

2010

Language:

english

File:

PDF, 197 KB

english, 2010

26

Early assessment of rapidly progressive interstitial pneumonia associated with amyopathic dermatomyositis

Eishi Miyazaki, Masaru Ando, Tomoko Muramatsu, Tetsujiro Fukami, Osamu Matsuno, Shin-ichi Nureki, Takuya Ueno, Tomiyasu Tsuda, Toshihide Kumamoto

Journal:

Clinical Rheumatology

Year:

2007

Language:

english

File:

PDF, 192 KB

english, 2007

27

Minocycline for the treatment of sarcoidosis: is the mechanism of action immunomodulating or antimicrobial effect?

Eishi Miyazaki, Masaru Ando, Tetsujiro Fukami, Shin-ichi Nureki, Yoshinobu Eishi, Toshihide Kumamoto

Journal:

Clinical Rheumatology

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

28

Successful treatment with tacrolimus of progressive interstitial pneumonia associated with amyopathic dermatomyositis refractory to cyclosporine

Masaru Ando, Eishi Miyazaki, Mari Yamasue, Yukiko Sadamura, Toshihiro Ishii, Ryuichi Takenaka, Takeo Ito, Shin-ichi Nureki, Toshihide Kumamoto

Journal:

Clinical Rheumatology

Year:

2010

Language:

english

File:

PDF, 128 KB

english, 2010

29

Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis

Nobutoshi Ito, Osamu Nureki, Mikako Shirouzu, Shigeyuki Yokoyama, Fumio Hanaoka

Journal:

Year:

2003

Language:

english

File:

PDF, 527 KB

english, 2003

30

Crystal structure of human DAAM1 formin homology 2 domain

Masami Yamashita, Tomohito Higashi, Shiro Suetsugu, Yusuke Sato, Tomoyuki Ikeda, Ryutaro Shirakawa, Toru Kita, Tadaomi Takenawa, Hisanori Horiuchi, Shuya Fukai, Osamu Nureki

Journal:

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

31

Amoxapine-associated acute respiratory distress

Masaru ANDO, Eishi MIYAZAKI, Ryu-ichi TAKENAKA, Toshiyuki OKUBO, Osamu MATSUNO, Shin-ichi NUREKI, Kazunobu ITO, Tomiyasu TSUDA, Toshihide KUMAMOTO

Journal:

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

32

Osteopontin levels are elevated in patients with eosinophilic pneumonia

Takuya UENO, Eishi MIYAZAKI, Masaru ANDO, Shin-ichi NUREKI, Toshihide KUMAMOTO

Journal:

Year:

2010

Language:

english

File:

PDF, 1.12 MB

english, 2010

33

10.1038/84927

Sekine, Shun-ichi, Nureki, Osamu, Shimada, Atsushi, Vassylyev, Dmitry G., Yokoyama, Shigeyuki

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 1.45 MB

english, 2001

34

Molecular basis for maintenance of fidelity during the CCA-adding reaction by a CCA-adding enzyme

Toh, Yukimatsu, Numata, Tomoyuki, Watanabe, Kazunori, Takeshita, Daijiro, Nureki, Osamu, Tomita, Kozo

Journal:

The EMBO Journal

Year:

2008

Language:

english

File:

PDF, 1.45 MB

english, 2008

35

Mechanism for the definition of elongation and termination by the class II CCA-adding enzyme

Toh, Yukimatsu, Takeshita, Daijiro, Numata, Tomoyuki, Fukai, Shuya, Nureki, Osamu, Tomita, Kozo

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 2.35 MB

english, 2009

36

Mg2+-dependent gating of bacterial MgtE channel underlies Mg2+ homeostasis

Hattori, Motoyuki, Iwase, Norihiko, Furuya, Noritaka, Tanaka, Yoshiki, Tsukazaki, Tomoya, Ishitani, Ryuichiro, Maguire, Michael E, Ito, Koichi, Maturana, Andres, Nureki, Osamu

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 1.36 MB

english, 2009

37

Structural basis for template-independent RNA polymerization

Tomita, Kozo, Fukai, Shuya, Ishitani, Ryuichiro, Ueda, Takuya, Takeuchi, Nono, Vassylyev, Dmitry G., Nureki, Osamu

Journal:

Year:

2004

Language:

english

File:

PDF, 491 KB

english, 2004

38

Snapshots of tRNA sulphuration via an adenylated intermediate

Numata, Tomoyuki, Ikeuchi, Yoshiho, Fukai, Shuya, Suzuki, Tsutomu, Nureki, Osamu

Journal:

Year:

2006

Language:

english

File:

PDF, 848 KB

english, 2006

39

Complete crystallographic analysis of the dynamics of CCA sequence addition

Tomita, Kozo, Ishitani, Ryuichiro, Fukai, Shuya, Nureki, Osamu

Journal:

Year:

2006

Language:

english

File:

PDF, 843 KB

english, 2006

40

Crystal structure of the MgtE Mg2+ transporter

Hattori, Motoyuki, Tanaka, Yoshiki, Fukai, Shuya, Ishitani, Ryuichiro, Nureki, Osamu

Journal:

Year:

2007

Language:

english

File:

PDF, 721 KB

english, 2007

41

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

Sato, Yusuke, Yoshikawa, Azusa, Yamagata, Atsushi, Mimura, Hisatoshi, Yamashita, Masami, Ookata, Kayoko, Nureki, Osamu, Iwai, Kazuhiro, Komada, Masayuki, Fukai, Shuya

Journal:

Year:

2008

Language:

english

File:

PDF, 959 KB

english, 2008

42

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

Sato, Yusuke, Yoshikawa, Azusa, Yamagata, Atsushi, Mimura, Hisatoshi, Yamashita, Masami, Ookata, Kayoko, Nureki, Osamu, Iwai, Kazuhiro, Komada, Masayuki, Fukai, Shuya

Journal:

Year:

2008

Language:

english

File:

PDF, 72 KB

english, 2008

43

Pyrrolysyl-tRNA synthetase–tRNAPyl structure reveals the molecular basis of orthogonality

Nozawa, Kayo, O’Donoghue, Patrick, Gundllapalli, Sarath, Araiso, Yuhei, Ishitani, Ryuichiro, Umehara, Takuya, Söll, Dieter, Nureki, Osamu

Journal:

Year:

2008

Language:

english

File:

PDF, 940 KB

english, 2008

44

Structural basis for translational fidelity ensured by transfer RNA lysidine synthetase

Nakanishi, Kotaro, Bonnefond, Luc, Kimura, Satoshi, Suzuki, Tsutomu, Ishitani, Ryuichiro, Nureki, Osamu

Journal:

Year:

2009

Language:

english

File:

PDF, 648 KB

english, 2009

45

Functional convergence of two lysyl-tRNA synthetases with unrelated topologies

Terada, Takaho, Nureki, Osamu, Ishitani, Ryuichiro, Ambrogelly, Alexandre, Ibba, Michael, Söll, Dieter, Yokoyama, Shigeyuki

Journal:

Natural Structural Biology

Year:

2002

Language:

english

File:

PDF, 2.46 MB

english, 2002

46

Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion

Kobayashi, Takatsugu, Nureki, Osamu, Ishitani, Ryuichiro, Yaremchuk, Anna, Tukalo, Michael, Cusack, Stephen, Sakamoto, Kensaku, Yokoyama, Shigeyuki

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 1.55 MB

english, 2003

47

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

Nishimasu, Hiroshi, Okudaira, Shinichi, Hama, Kotaro, Mihara, Emiko, Dohmae, Naoshi, Inoue, Asuka, Ishitani, Ryuichiro, Takagi, Junichi, Aoki, Junken, Nureki, Osamu

Journal:

Nature Structural and Molecular Biology

Year:

2011

Language:

english

File:

PDF, 2.09 MB

english, 2011

48

A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase

Kise, Yoshiaki, Lee, Sang Won, Park, Sang Gyu, Fukai, Shuya, Sengoku, Toru, Ishii, Ryohei, Yokoyama, Shigeyuki, Kim, Sunghoon, Nureki, Osamu

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 1.21 MB

english, 2004

49

Structural basis for anticodon recognition by methionyl-tRNA synthetase

Nakanishi, Kotaro, Ogiso, Yuri, Nakama, Takashi, Fukai, Shuya, Nureki, Osamu

Journal:

Nature Structural and Molecular Biology

Year:

2005

Language:

english

File:

PDF, 242 KB

english, 2005

50

Crystal structures of leucyl/phenylalanyl-tRNA-protein transferase and its complex with an aminoacyl-tRNA analog

Suto, Kyoko, Shimizu, Yoshihiro, Watanabe, Kazunori, Ueda, Takuya, Fukai, Shuya, Nureki, Osamu, Tomita, Kozo

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 438 KB

english, 2006